[Question #9011] Testing Question

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37 months ago
Hi Drs,

Thank you for this valuable service. For syphillis what is the testing window always six weeks or is it different if there are or are not symptoms? If there are symptoms is the testing window a few days after, a week after or six weeks after? Thank you
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Edward W. Hook M.D.
37 months ago
Welcome to our forum. Thanks for your questions. I’ll be glad to provide the information you desire.  FYI, I happen to be on the forum at the time your question arrived and so you are receiving your response far more quickly than is the norm for the forum. Subsequent follow-up questions may take 12 or more hours for a response to be posted.

When person who has acquired syphilis develop primary, ulcerative lesions at a site of inoculation, blood test for syphilis become positive within 2 to 4 days following the appearance of the lesion, irrespective of when or where the lesion appeared.  Other signs of later stages of syphilis such as a rash or swollen lymph glands are always accompanied with positive blood test at the time they appear or are detected.

Not all persons who acquire syphilis however are aware of developing signs or symptoms of infection which lead them to seek care. In this circumstance, persons who may have been exposed to a sexual partner with Syphilis will have definitive test results six weeks following their last encounter. Blood tests that are negative for syphilis infection at any time more than six weeks following a potential encounter in which syphilis may have been acquired are conclusively negative and there is not a need for further testing.

I hope this information is helpful. EWH
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36 months ago
Thank you, for the information and clearing up the testing question.  That blood tests would become positive 4 days after a chancre. 

Is Syphillis passed via bodily fluids or strictly through direct contact with a sore? Also how is it transmitted in later stages? Thank you again for the information that you provide on this site. Have a nice day. 
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Edward W. Hook M.D.
36 months ago
In nearly allocation syphilis is transmitted by direct contact with an infectious lesion. The bacteria can be found in the blood using research techniques and before the era of modern blood banking the bacterium was occasionally transmitted through transfusions however, with modern blood banking that is no longer the case. Syphilis becomes less infectious in the later stages and in the absence of lesions is not transmissible through sexual contact.  EWH ---