[Question #9353] Testing after PEP

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33 months ago
Thank you doctors for your help previously regarding HPV, you were right and my pap came back “normal”

Now I currently have a question about HIV testing and PEP

A few months ago I was sexually assaulted (my vagina was momentarily penetrated with a penis without a condom when it happened). I took my first dose of PEP around 16 hours after it occurred. I threw up a dose on the first week and I threw up a second dose on the third week, not sure if that makes that PEP less effective. I tested 13 days post PEP with an RNA test that came back negative. I then tested 41 days post PEP with an Ag/Ab test that also came back negative. 

Can I consider my status conclusively negative for HIV with these tests or would you recommend anymore? I am looking to start a sexual relationship with my new partner and although we plan on using condoms I do not want to accidentally put him at risk for anything. 

Are my tests post PEP conclusive? 

Thank you. 
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Edward W. Hook M.D.
33 months ago
Welcome back to the Forum.  Thanks for providing the results of your PAP smear- I'm pleased but not surprised at the result.

I'm sorry to hear of your sexual assault and hope that your recovery, which a process, not an event, is moving forward.  I'm pleased to tell you that as part of that recovery process you can be confident that you did not acquire HIV from the assault.  The combination of your PCR test 13 days following PEP followed by an negative combination Ag/Ab test at day 41 is conclusive.  You did not get HIV and there is no need for further testing.

Hope this message is helpful.  EWH
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33 months ago
Thank you so even with taking PEP for 30 days (and having missed two doses) I can be sure that my RNA test taken 13 days after PEP and ag/ab 41 days after PEP are both conclusive? 

I can be 100% certain that I am in the clear and negative of HIV? Again I am looking to start relations and don’t want to pose a risk to anybody. 
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Edward W. Hook M.D.
33 months ago
Correct.  Be confident that you did not get HIV from the encounter that led you to take PEP.  EWH---
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33 months ago
Thank you I will listen to your expertise and trust that my results are conclusive. 

Unfortunately circling back to HPV, I’ve had two bumps show up on my outter vagina lips. One looks like a black head (now an inflamed blackhead) and the other looked like a boil or infected ingrown hair (it’s now a pustule), I’m not sure if they are warts and I’ve sent pictures to my gyno for her opinion. My concern is that I had two skin tag like/ sort of pimple bumps show up bordering on my inner thigh and buttcheek about 2 years ago. The last time I had sex was 3 years ago. Is it possible for these to be genital warts? Again I haven’t had sex in 3 years and I’ve had the first guardasil HPV vaccine. 


If these are warts what is the protocol for entering a New Romantic relationship? Are we meant to disclose if we don’t have a current wart? Is there a time we should wait after the wart to prevent spreading? Do condoms help? Thank you in advance. 
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33 months ago
Also wanted to clarify 

-the bumps I got three years ago on my upper thigh/lower buttcheek were red 

-I was vaccinated with Guardasil 4 for HPV years before my first time having sex
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Edward W. Hook M.D.
33 months ago
I'm sorry you continue to worry so much about HPV.  As I mentioned earlier, it is unlikely that the bumps you have noted are HPV- they certainly do not sound like typical warts and your past HPV vaccination (with Gardasil 4) provides a high degree of protection against the two HPV types that cause most visible warts.  I presume you'll ask your doctor to take a look.  In general direct examination is preferable to pictures.  

When you enter a new romantic relationship, there are several things I would suggest:
1. Early on, condoms are a good idea.
2. To date you have not had proven HPV.  You might start the conversation with a prospective partner by mentioning that you've been vaccinated against HPV and ask if your partner has as well.  This might then provide the opportunity to ask if they've ever had an STI (the reply should not be a deal breaker if you like the person but it allows for open conversation which is good for any relationship)
3.  If the relationship is going forward, some clients find suggesting that both persons go together for testing (it should be available at little or no cost from your local health department, irrespective of insurance status)

I hope these replies have been helpful.  As you know, we provide up to three responses to each clients questions.  Thus this 3rd response will be my final one and the thread will be closed shortly without further replies.  Try not to worry so much about HPV, it really is not that big a deal even if you should happen to acquire it.  EWH
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33 months ago
Thank you I would like to go in person but the rate of appointments for specialists I can’t guarantee they’d still be active by the time my appointment comes. These blemishes usually go away in a couple of days for me (around 6)

Do the placements of these blemishes correspond with typical warts? They’ve always shown up on a different location each time although still in the groin region. 

Also is HPV testing available for men and women under 30? If things get physical should I disclose these blemishes?  Thank you
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33 months ago
Also did you mean my current pustule blemishes don’t seem like common warts or the red bumps I got two years ago? Or both? Thank you. 
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Edward W. Hook M.D.
33 months ago

Are you intentionally ignoring that this thread was supposed to be closed?

If the lesions are not there in a few days, it is not HPV.

You are displaying sign of unwarranted HPV anxiety.  If you cannot control it you should seek counseling.  EWH 
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