[Question #9485] HPV wart post treatment questions

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32 months ago
Dear doctor i hope you are doing fine, let me start by giving you context, about a year ago i had my warts treated with electrocautery and have never seen them again, so i wanted to ask you a couple of questions regarding that info
1- since the virus only affects the epidermis which got burnt by the electrocautery and its been that much time with it not coming back which seems to indicate that no areas of the infected skin where missed during the procedure. Does that mean that i need to stop worrying about recurrence since its practically impossible for it to recur since the virus has been technically destroyed with this particular procedure?
Based on your response i will write my next question, thank you.
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H. Hunter Handsfield, MD
32 months ago
Welcome to the forum. I'm happy to address this question. Unfortunately, the answer these questions isn't completely clear.

With no visible recurrence of your genital warts after a year, it is probable that the problem is gone and that you are no longer infectious, i.e. no longer able to transmit the HPV strain that caused the warts to yoru sexual partner(s). However, there is no guarantee, and no way to be completely certain. It seems you know that even normal appearing skin can be infected with HPV, and genital warts can be viewed sort of like an iceberg:  that is, HPV causing warts can be more widespread than the visible warts themselves. However, it also is true that absence of recurrent visible warts makes it likely the infeciton is gone.

So most likely the problem is gone, will not recur, and cannot be transmitted to sex partners. But it just isn't possible to be certain.

I hope this information is helpful. Let me know if anything isn't clear.

HHH, MD
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32 months ago
oh i understand now, thats good to hear. so in a few months i will be undergoing HgH therapy with the hormone injection, because i read it affects the body cells will it affect in anything in regards to my case, or theres no correlation between them? 
thanks for your time Dr. Handsfield.
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H. Hunter Handsfield, MD
32 months ago
I am unaware of any evidence or scientific reports that human growth hormone has any effect on HPV, its reactivation, etc. No worries!---
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32 months ago
Thank you for the reassurence Dr. For my third and final question i would like to ask you for your opinion on 2 things: 
1-Why is it said that the wart causing hpv types are low cancer risk, when it clearly multiplies skin cells, but high risk cancer hpv types dont create warts?
2-Why do some people have warts and others dont is it purely based on the type of hpv you contracted or are there other factors at play in determining if a wart develops or not, like genetics, environment, etc.?
thank you for taking your time answering all my questions Dr. Handsfield. 
i wish you a good new year, kind regards.

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H. Hunter Handsfield, MD
32 months ago
1. Sophisticated HPV biology scientists might know why specific HPV types are more or less likely to cause warts, versus cancer, or not abnormal cell growth at all. However, I do not. Sorry.

2. There are no known reasons for the variable frequency with which the same HPV types do or don't cause various manifestations in different persons. It is logical that there might be subtle but unknown differences in immune systems responses from one person to the next. Dose of HPV might make a difference.

That completes the two follow-up exchanges included with each question and so ends this thread. Sorry I couldn't answer these particular questions as completely as we both would like, but I hope the discussion as a whole has been helpful. Best wishes and stay safe.
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