There are several reasons I am confident you have no STD. Oral to skin exposure is free of STD risk on any part of the body; the skin of the scrotum is no more susceptible to infection than anywhere else on the body. Even if your partner had an STD, there is nothing that you would have acquired. The physical nearness of the testicle doesn't mean infection can pass through the skin directly to the testis; to reach the testis an infection would have to enter the bloodstream and then happen to settle in the testicle by chance. To state it another way, from a biological/infection perspective, the testicle is no closer to the skin of the scrotum than is, say, your brain or a kidney.

As for your testicular pain and swelling -- whether orchitis, epididymitis, or something else -- I suppose it is possible that trauma from the vigor of the exposure could be a contributing factor. However, the timing isn't right; trauma would have caused pain and swelling within hours, not 10 days later. I have to believe that symptom was unrelated to the events you have described. Did you have any other sexual exposures in the 2-3 months before onset of the testicular pain? Did you ever have any discharge from the penis or painful urination? I ask because epididymitis, due to either STD or urinary tract infection, always are considerations for otherwise unexplained testicular pain and swelling.

Your scrotal skin inflammation:  The earliest symptoms might have been just local skin irritation from the vigorous oral exposure. After that, itching and irritation have several potential causes, but STDs are not among them. Herpes doesn't behave at all like this, and your negative HSV blood tests prove you don't have HSV.

Shingles? Wow -- that's a surprise diagnosis. But if that's an accurate diagnosis at present, it has nothing to do with the exposure described and has not been present ever since that event. Shingles doesn't last for months and is not caught from another person; it results from reactivation of the varicella zoster virus (VZV), the cause of childhood chickenpox. Certain immune deficiencies raise the risk of shingles, but it's also common in people with entirely normal immune systems. (I've had it, and my son had shingles at age 14.)

Finally, HIV? It isn't possible. First, it is never transmitted by oral-skin contact. Second, your negative HIV tests are conclusive.

Those comments pretty well cover your specific questions, but to assure no misunderstanding:

Q1. There is no such thing as HIV (new strains or otherwise) that could give negative blood tests or cause the sorts of problems you have had. As noted above, shingles does not necessarily mean you have HIV or any other immune deficiency. 

Q2, Q5. You acquired no STD and have no STD now and nothing you can pass to a sex partner.

Q3, Q4. You do not have HIV. There is no possibility of not making HIV antibodies within a few weeks of infection. And anyway, your tests included not just HIV antibody, but also were negative for the virus itself (the RNA test and the Ag component of the AgAb test).

I hope these replies settle your concerns about HIV and other STDs. As for your apparent shingles and the ongoing scrotal irritation, you'll need to continue to work with your dermatologist. I have no further advice about them.

Please let me know if anything isn't clear. Best wishes.

HHH, MD

I never had any issue with scrotum prior to this exposure.

My worries was HSV and HIV. I know you can get HSv from oral and most folks get it within 10 days so apparent symptoms at 10 day in genital really got me worried.

Derma was too surprise culture came back as zoaster from labcorp viral culture.

. He said he never seen it on scrotum in 40 years as Derma.

So really I'm worried what HSV / HIV / STD I got that I can't seem to clear the redness, on and off itching, tingling sensation in scrotum and groin.

One thing I didn't mentioned was prior to the exposure I was on Humira for 3 months. As soon as I had the encounter I stopped taking arthritis shot - Humira.

Could Humira delay HIV / HSV antibodies? 

" I can't seem to clear the redness, on and off itching, tingling sensation in scrotum and groin." These symptoms are not typical of herpes. And herpes outbreaks never last more than a week or two.

The location is fine for herpes zoster, which can occur anywhere on the body. However, most of what you describe doesn't fit well with it. Seems to me that the positive test may be false.

However, as I said at the outset, I am confident you have no STD. Therefore, I have no further advice about your symptoms or test results. Sorry.

Most importantly, I took Valtrex and my symptoms improved (while on it)....21g but few days later started having itching and crawling sensation back again...Anyhow...given a negative blood work and neg for HIV I will take it home and move on with that. 

Final Question;

Based on what I've said so far is it safe / normal to resume sexual activity with regular partner without worrying about passing anything on? I know you can't guarantee anything but based on what I've said so far on my context and negative testing for 

RPR, HIV , HSV 1/2 and G&C . 

I think I've tested properly way out of the window period allowing ample time for any of the test to be positive.

You should have been continuing your normal sexual life the last 10 months. It certainly is safe and appropriate to do so now. And yes, all tests were done sufficiently long to have given positive results if you had any of those conditions.

That completes the two follow-up exchanges included with each question and so ends this thread. I hope the discussion has been helpful.